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Bextra Glossary

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Bextra and Cardiovascular Events
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Bextra and Toxic Epidermal Necrolysis(TEN)
Bextra and Stevens-Johnson Syndrome(SJS)
Bextra and Erythema Multiforme
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Erythema Multiforme
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Bextra Glossary

Bextra Glossary

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Bextra – An NSAID that falls into the “COX-2 Inhibitory category.

COX-1 – short for Cyclooxygenase-1, which is an enzyme that shields delicate stomach tissue from harsh digestive acid

COX-2 – short for Cyclooxygenase-2, which is an enzyme found in inflamed and feverish tissues that causes pain and discomfort.

COX-2 Inhibitor – a drug that selectively blocks COX-2 and leaves COX-1 alone, thereby relieving inflammation without causing stomach irritation and bleeding

Erythema Multiforme – a mild skin allergy characterized by small, ring shaped rashes on the hands and arms and accompanied by flu-like symptoms.

Heart Attack – a cardiovascular event caused by either a blockage in an artery or death of heart tissue due to lack of oxygen

NSAID – a Non-Steroidal Anti-Inflammtory Drug, such as asipirn and ibuprofen, commonly used to reduce swelling and relieve mild to moderate pain.

Stevens-Johnson Syndrome (SJS) – a potentially fatal allergic reaction that causes the mucus membranes under the skin to become inflamed and irritated, resulting in great pain and scarring.

Stroke – a “brain attack” that results from lack of oxygen to the brain caused by an arterial clog or a ruptured intracranial blood vessel. Strokes often cause brain damage, memory problems, and death.

Toxic Epidermal Necrolysis (TENS) – an extremely fatal skin disorder that causes the skin to flake off and shed in large sheets. It is considered a more advanced form of Stevens-Johnson Syndrome.


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